"Search for sources of resistance to anthracnose in White Lupin – Combining -Omics & Genome editing to identify key breeding targets"
(contact: Prof. Cécile BEN, C.Ben@skoltech.ru, GenTech collaborative project)

Anthracnose agent Colletotrichum spp. has been listed one of the top ten fungal pathogens of scientific and economic importance. Infected lupin fields with C. lupini can cause significant yield loss, 0.1% of infected seeds resulting in more than 50% yield loss. Lupin's lack of resistance to C. lupini restricts its use in rotation systems.
The main goal of the project is to implement -Omics and genome editing to identify new genetic sources of resistance to anthracnose in white lupin.

The specific goals will be :
1. To carry out a multi-omics analysis of the response to Colletotrichum lupini infection in Resistant & Susceptible cultivars. The proteomics data to be obtained at Skoltech Agro will be supplemented by transcriptomics and metabolomics data to be obtained by our partners from RIRAE.

2. To implement an integrative biocomputational analysis of the multi-omics data to reveal candidate genes for resistance to anthracnose

3. To perform the functional validation of most promising candidate genes using Genome-Editing (GE)

Skills: Bioinformatics for -omics data analysis, molecular biology (incl. cloning), Plant biotechnology (ie in vitro culture, experience in plant genetic transformation or genome editing would be a plus), basic knowledge in phytopathology.

You must apply through the entire Skoltech admissions process in order to be considered for the aforementioned PhD position.

Deadline: Sunday, July31, 2022
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